2013 Fiscal Year Final Research Report
Do epigenetics influences the form of a mandibular beyond the generation.
| Project/Area Number |
24792284
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 歯科矯正学 / 顔面形態 |
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| Research Abstract |
A rat fed with soft diet changes its cranial and mandibular form compared to a rat fed with hard diet. In this time, we assess the analysing method for the form of mandibular with advancing 3DCT and orthodontics cephalometric analysis. As a result, we could detect refined change of mandibular form in mice between grown with powdery feed and with fixed hard feed.
Additionally, we analysed gene expression in masseter muscles in these two group mice. Some gene expression were significantly changed between these two groups. Further more, I find outthe reaction of MYH genes expression which play a role in deciding a character of muscle.
These finding showes that the hardness of feed may influence to the form of mandibular via the change of chalacter of masseter muscle.
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Research Products
(7 results)
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[Journal Article] Gap-junction-mediated Communication in Human Periodontal Ligament Cells2013
Author(s)
Y Ishihara, N Kawanabe, K Sumiyoshi, Y Yoshikawa, M Nakamura, Y Imai, T Yanagita, H Fukushima, H Kamioka, T Takano-Yamamoto, T Yamashiro
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Journal Title
Journal of Dental Reserch
Volume: 92
Pages: 635-640
DOI
Peer Reviewed
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