2014 Fiscal Year Final Research Report
Mastication habits promote development of liver function through myokines
| Project/Area Number |
24792348
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Social dentistry
|
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | 食習慣 / 糖代謝 / IL-6 |
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| Outline of Final Research Achievements |
Since obesity and diabetes are becoming increasingly prevalent in childhood, various problems associated with dietary habits-such as excessive eating of so-called soft food or fast food-are now matters of worldwide concern. However studies have revealed the mechanism that connects the eating habits and systemic metabolic disorder is not allowed yet. In this study, mice were fed with pellet- or powder-food from wearing until 6 months of age, the long-term eating of powdered food induced hyperglycemia and systemic-illness signs through myokines produced from masseter muscle. Among daily dietary habits, mastication of food of adequate hardness is an very important environmental factor in growth and development of an individual through the development of liver function.
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| Free Research Field |
歯科矯正学
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