2013 Fiscal Year Final Research Report
Development of nitrogen–boron bond cleavage reaction and its application to practical synthesis of multifunctional compounds
| Project/Area Number |
24850011
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Organic chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
KENSUKE Kiyokawa 大阪大学, 工学(系)研究科(研究院), 助教 (80632364)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Keywords | 有機化学 / 合成化学 / アミノホウ素化 / アミノボラン / ホウ素 |
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| Research Abstract |
Suitable aminoboranes has been designed, and indeed, we succeeded in synthesizing and isolation of several aminoboranes. We next investigated the cleavage of nitrogen-boron bond of the aminoborane followed by aminoboration of carbon-carbon multiple bond moieties such as alkenes and alkynes by using transition metal catalysts. Although extensive screening of metal catalysts such as Pd, Pt, and Cu catalysts in combination with ligands was conducted, the effective catalyst system has not been established yet. However, the present study provided new insights into organic synthesis using aminoboranes.
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