2013 Fiscal Year Final Research Report

ESA therapy and vitamin D supplementation in kidney transplant recipients

Research Project

Project/Area Number	24890109
Research Category	Grant-in-Aid for Research Activity Start-up
Allocation Type	Single-year Grants
Research Field	Kidney internal medicine
Research Institution	Osaka University
Principal Investigator	HAMANO Takayuki 大阪大学, 医学(系)研究科(研究院), 寄附講座助教 (50403077)
Project Period (FY)	2012-08-31 – 2014-03-31
Keywords	移植後貧血
Research Abstract	In recruiting patients, the anemia in Japanese renal transplant patients proved to be mild unlike the counterparts in the western countries and we found relatively low percentage of patients meeting the enrollment criteria. Therefore, we began to enroll patients in new facilities in addition to planned facilities. The baseline results of 96 patients enrolled so far are as follows. Mean dialysis vintage prior to transplantation was 6 years, mean creatinine was 1.96 mg/dL, and mean hemoglobin was 11.0 g/dL. Half of the patients received long-acting ESA. Mean ferritin was 149 ng/mL and TSAT was 36% possibly due to the fact that iron repletion is the enrollment criteria. As a result of enrolling relatively severe anemia, mean urinary protein was 0.99 g/gCr, which is much higher than expected. We are still enrolling patients while we are doing intervention in enrolled patients.

(1 results)