2013 Fiscal Year Final Research Report
The study on mechanism elucidation for the effects of small vibration stimuli on bone formation
| Project/Area Number |
24890162
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
KONO Takashi 九州大学, 大学病院, 医員 (70636068)
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| Project Period (FY) |
2012-08-31 – 2014-03-31
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| Keywords | インプラント / 振動刺激 / 骨形成促進 |
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| Research Abstract |
The effects of small vibration stimuli on bone formation have been reported. The present in vitro study assessed the effect of low-magnitude, high-frequency (LMHF) vibration stimuli for bone formation on gene expression.
In the rat osteoblast-like cells, LMHF vibration stimuli can enhance the bone formation by increasing some factors which accelerate bone formation and decreasing the factor which inhibits bone formation.
However, in the mouse osteocyte (MLO-Y4), no gene significantly changed between control group and vibration group.
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