2016 Fiscal Year Final Research Report
Elucidation of performance-associated functional polymorphisms in sprinters and endurance runners in the world and Japan
| Project/Area Number |
25242062
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology |
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Principal Investigator |
Tanaka Masashi 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (60155166)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 運動能力 / 持久力 / 瞬発力 / 有酸素運動能力 / 無酸素運動能力 / 全ゲノム領域関連解析 / 全ゲノム塩基配列決定 |
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| Outline of Final Research Achievements |
We analyzed 240K functional SNPs in 4150 Japanese controls by use of HumanExome BeadChip. We also analyzed functional SNPs in 93 Jamaican sprinters and 306 controls as well as 112 American sprinters and 200 controls after whole genome amplification (WGA). The genotyping error rates were markedly high for the samples after WGA. Therefore, we selected 8 Ethiopian and 8 Kenyan endurance runners, re-extracted DNA from their buccal swab samples, and started whole genome re-sequencing analysis.
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| Free Research Field |
ゲノム科学
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