Study on paper micro analysis chip and the system integration

2015 Fiscal Year Final Research Report

• Project/Area Number: 25249027
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Intelligent mechanics/Mechanical systems
• Research Institution: The University of Tokyo
• Principal Investigator: Miyake Ryo 東京大学, 工学(系)研究科(研究院), 教授 (50417052)
• Co-Investigator(Kenkyū-buntansha): FUNAHASHI hisakage 広島大学, サステナブル・ディベロップメント実践研究センター, 特任講師 (60552429)
• Co-Investigator(Renkei-kenkyūsha): KURODA Akio 広島大学, 先端物質科学研究科, 教授 (50205241)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: マイクロ流体デバイス / 紙 / 医用検査装置 / 情報機構

Outline of Final Research Achievements

The purpose of this study is to enhance analysis-chip technologies based on paper material to allow us to reduce manufacturing cost and environmental load caused by medical wastes. We were aiming at developing a detection method for small amount of sample on a paper analysis chip and prototyping an automatic analysis system in order to envision problems and propose solutions towards practical use. Consequently, a micro detection cell for an absorptiometry with thermal lens effect and thin gold electrodes (t=100~150nm) for an alternating current impedance measurement (10kHz) were designed and fabricated on paper chips. They allowed us to measure an absorbance (644nm) of trace amount of sample (~1uL) and signal related to electrolyte (Na＋) in the sample. In addition, we prototyped an automatic analysis system with including newly developed detectors, reagent dispensers, paper-chip precision positining mechanism etc. This system successfully demonstrated cooperative automatic operation.

Free Research Field

MEMS