2016 Fiscal Year Final Research Report
Studies on RNA-mediated regulatory systems promoting plant meiosis
Project/Area Number |
25252004
|
Research Category |
Grant-in-Aid for Scientific Research (A)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Science in genetics and breeding
|
Research Institution | National Institute of Genetics |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
MIYAZAKI Saori 国立遺伝学研究所, 実験圃場, 助教 (40390687)
TSUDA Katsutoshi 国立遺伝学研究所, 実験圃場, 助教 (30756408)
|
Research Collaborator |
KOMIYA Reina
LIU Hua
MIMURA Manaki
EIGUCHI Mitsugu
KUMU Rise
FURUYA Noriko
MAKINO Tomomi
|
Project Period (FY) |
2013-04-01 – 2017-03-31
|
Keywords | 減数分裂 / イネ / 植物 / small RNA / Argonaute / RNA / 組み換え / 生殖 |
Outline of Final Research Achievements |
Meiosis is an important biological event that produces genetic diversity of eukaryotes. This project analyzed molecular functions of three rice proteins important for meiosis progression. MEL2 controls meiotic entry in rice. We identified the RNA consensus sequence that MEL2 preferentially bound in vitro, and predicted the genes under the control of MEL2. Next, the analyses of germline-specific Argonaute MEL1 and anther tapetum-specific transcription factor EAT1 revealed possibilities that small RNAs regulated male meiosis non-cell autonomously, and triggered chromosome remodeling in male meiocytes. These findings unveiled that RNA-mediated epigenetic regulatory mechanisms play essential roles in progression of plant meiosis.
|
Free Research Field |
植物生殖遺伝学
|