2015 Fiscal Year Final Research Report
LAL-free LPS detection device by using a nanocarbon film electrode
| Project/Area Number |
25288071
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
Kato Dai 国立研究開発法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 (80533190)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIOKA Kyoko 国立研究開発法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 (50358321)
SUZUKI Yoshio 国立研究開発法人産業技術総合研究所, 健康工学研究部門, 主任研究員 (60321907)
TANAKA Mutsuo 国立研究開発法人産業技術総合研究所, 健康工学研究部門, 研究グループ長 (70344108)
NIWA Osamu 埼玉工業大学, 先端科学研究所, 教授 (70392644)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | ナノカーボン / 電気化学 / LPS / デバイス / エンドトキシン |
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| Outline of Final Research Achievements |
We developed electrochemical lipopolysaccharide (LPS) detection systems based on a nanocarbon film electrode. We also developed new LPS probes consisting of LPS-affinity molecules and electroactive compounds. The nanocarbon film electrode allowed us to obtain the electrochemically amplified signals, which was dependent on the amount of LPS. The detection limit was 200 pg/mL of LPS even without a conventionally available reagent for LPS detection.
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| Free Research Field |
分析化学、電気化学
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