2015 Fiscal Year Final Research Report
Elucidating salvaging role of tissue-specific organelle DNA degradation conserved in land plants
| Project/Area Number |
25291063
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plant molecular biology/Plant physiology
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
Tsuneaki TAKAMI 岡山大学, 資源植物科学研究所, 技術職員 (70614254)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 葉緑体 / ミトコンドリア / オルガネラ分化 / DNA分解 / 葉老化 / ステイグリーン / ヌクレアーゼ |
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| Outline of Final Research Achievements |
Chloroplasts and mitochondria are the organelles that originate from endosymbiosis of respective ancestral bacteria and retain their own DNA as a remnant. Although these organelle DNAs are very limited as genetic content, they exist as multi-copy and vary in the amount. Moreover, tissue-specific degradation of organelle DNAs has been reported in literature since two decades ago but little is understood at the molecular level. Recently, our group identified DPD1 exonuclease, which is conserved in land plants, be dual targeted to plastids and mitochondria, and appear to degrade organelle DNA.
In this study, we attempted to corroborate the role of DPD1 in organelle DNA degradation. We focused on leaf senescence and examine the possibility that organelle DNA degradation is related to nutrient salvage.
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| Free Research Field |
植物分子生物学・遺伝学
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