Elucidation of the mechanism of neoatherosclerosis

2015 Fiscal Year Final Research Report

• Project/Area Number: 25293182
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Cardiovascular medicine
• Research Institution: Kyoto University
• Principal Investigator: KIMURA Takeshi 京都大学, 医学(系)研究科(研究院), 教授 (80359786)
• Co-Investigator(Kenkyū-buntansha): ONO Koh 京都大学, 大学院医学研究科, 准教授 (00359275) ; NISHI Eiichiro 京都大学, 大学院医学研究科, 准教授 (30362528) ; SHIOI Tetsuo 京都大学, 大学院医学研究科, 講師 (50360095) ; MAKIYAMA Takeru 京都大学, 大学院医学研究科, 助教 (30528302) ; SAITO Naritatsu 京都大学, 大学院医学研究科, 助教 (20467484) ; IMAI Masao 京都大学, 大学院医学研究科, 助教 (10625677)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 動脈硬化 / ステント / 血栓 / 狭心症 / 心筋梗塞

Outline of Final Research Achievements

Percutaneous coronary intervention using coronary stent is a standard therapy for ischemic heart disease. Restenosis after stent implantation is dramatically reduced by the development of drug eluting stent. However, very late stent thrombosis and late catch-up phenomenon, which is the restenosis several years after treatment, are still remained as serious problems. Recently, neoatherosclerosis is receiving research attention for the cause of such conditions. We performed clinical and basic research to contribute the elucidation of the mechanism of neoatherosclerosis.

Free Research Field

循環器内科学