Development of new functional biomaterials with femtosecond laser

2015 Fiscal Year Final Research Report

• Project/Area Number: 25420777
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Material processing/Microstructural control engineering
• Research Institution: Osaka University
• Principal Investigator: TSUKAMOTO MASAHIRO 大阪大学, 接合科学研究所, 准教授 (90273713)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: フェムト秒レーザー / 酸化チタン膜 / エアロゾルビーム / 周期的微細構造 / 偏光制御 / 生体適合性 / 細胞試験

Outline of Final Research Achievements

Periodic nanostructures on TiO2 film were formed using a femtosecond laser with wavelengths of 258 nm (third harmonics), 388 nm (second harmonics) and 775 nm (fundamental), respectively. When the TiO2 film was irradiated with the femtosecond laser at 388 nm, the nanostructures with the period of 132 nm, 17 % of the fundamental wavelength of the femtosecond laser, was produced. Influence of the periodicity of the nanostructures on cell spreading was investigated. By changing the direction of the grooves of the nanostructures, cell spreading could be controlled. Effect of the curvature radius of the nanostructures’ grooves on cell spreading was also investigated.

Free Research Field

工学　材料工学　材料加工・組織制御工学　加工・熱処理　レーザー加工