2015 Fiscal Year Final Research Report
Multisynaptic pathway from retinal ganglion cells to visual areas V4 and MT
| Project/Area Number |
25430004
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Neurophysiology / General neuroscience
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
NINOMIYA TAIHEI 京都大学霊長類研究所, 統合脳システム分野, 研究員 (40586343)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Keywords | 狂犬病ウイルス |
|---|
| Outline of Final Research Achievements |
Employing retrograde transsynaptic transport of rabies virus, we analyzed the architecture of bottom-up pathways from retinal ganglion cells to ventral stream area V4 (visual area 4) and dorsal stream area MT /V5 (middle temporal area/visual area 5). Labeled cells were observed in reina. It was supposed that the connection from retinal ganglion cells to V4 or MT/V5 might have minimally trisyanptic or disyanptic manner, respectively.
In addition, from the side of pathophysiology, we investigated the case of higher visual dysfunction of dyschromatopsia and lack of stereopsis due to the rare encephalitis and reported the relationship between retina and higher visual areas. The retina and macular were not damaged even if cortical visual areas were functionally damaged.
|
| Free Research Field |
神経眼科
|
