Understanding the molecular mechanism underlying immune response via perception of viral pathogen-associated molecular pattern in plant

2015 Fiscal Year Final Research Report

• Project/Area Number: 25450055
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Plant protection science
• Research Institution: Hokkaido University
• Principal Investigator: NAKAHARA Kenji 北海道大学, (連合)農学研究科(研究院), 講師 (90315606)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 免疫受容体 / カルモジュリン様タンパク質 / RNAサイレンシング / 全身獲得抵抗性 / サリチル酸シグナリング / 植物ウイルス / RNAサイレンシング抑制タンパク質

Outline of Final Research Achievements

Tobacco calmodulin-like protein rss-CaM is shown to be an immune receptor to induce salicylic acid signaling via perception of viral RNA silencing suppressor and calcium influx as virus infection cues. We have previously revealed that rgs-CaM enforces antiviral RNA silencing by binding to and directing degradation of RNA silencing suppressors via autophagy. Here, we show the activation of this antiviral function of rgs-CaM by salicylic acid signaling. Our results suggest that these rgs-CaM functions contribute to systemic acquired resistance against virus.

Free Research Field

植物－ウイルス相互作用・植物自然免疫