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2015 Fiscal Year Final Research Report

Analysis and application of a new communication among oral bacteria using the conversion of autoinducer.

Research Project

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Project/Area Number 25450103
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Applied microbiology
Research InstitutionYamaguchi University

Principal Investigator

Azakami Hiroyuki  山口大学, 農学部, 教授 (40263850)

Co-Investigator(Renkei-kenkyūsha) NOIRI Yuichiro  大阪大学, 歯学研究科, 准教授 (50218286)
Research Collaborator Fariha Jasin Mansur  
MORISHIGE Natsumi  
TAKAHARA Sari  
Mohammad Minnatul Karim  
Project Period (FY) 2013-04-01 – 2016-03-31
Keywords歯周病原性細菌 / Eikenella corrodens / オートインデューサー / ポーリン / クオラムセンシング
Outline of Final Research Achievements

Microorganisms communcate each other using various chemical compounds as language. Most pathogenic bacteria control their pathogenesis by these communication.Thus, if we can block their communication, we may apply it to treatment or prevention to many diseases. In this study, we found and cahracterized a new factor to block the bacterial communication. It is very interesting that this factor can block the wide range of communication among bacteria.

Free Research Field

応用微生物学

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Published: 2017-05-10  

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