2015 Fiscal Year Final Research Report
Determination of bovine leukemia virus susceptible and resistant gene by the comparison of Japanese native cattle with Japanese Black cattle
| Project/Area Number |
25450405
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Animal production science
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
Takeshima Shin-nosuke 国立研究開発法人理化学研究所, 分子ウイルス学特別研究ユニット, 研究員 (60342812)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 日本在来牛 / ウシ主要組織適合遺伝子複合体（BoLA) / 疾患感受性 / ゲノムリシークエンス / 牛白血病ウイルス / 口之島牛 / 次世代シークエンサー / 見島牛 |
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| Outline of Final Research Achievements |
We sequenced bovine major histocompatibility complex region for 12 of Kuchinoshima cattle, 11 of Mishima cattle and 10 Japanese black cattle by target re-sequencing method using Next generation sequencer to determine whether the susceptible/resistant genotype for bovine leukemia virus were originated from Japanese native cattle or not. PCA analysis showed that susceptible gene were came from Japanese native cattle but resistant gene were introduced from foreign country.
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| Free Research Field |
免疫遺伝学
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