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2015 Fiscal Year Final Research Report

Immunohistochemical analysis of Thy-1 and PDGF in IgG4-related disease

Research Project

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Project/Area Number 25460465
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Human pathology
Research InstitutionKanazawa Medical University

Principal Investigator

KUROSE Nozomu  金沢医科大学, 医学部, 助教 (10319048)

Co-Investigator(Kenkyū-buntansha) Minato Hiroshi  金沢医科大学, 医学部, 教授 (10293367)
MASAKI Yasufumi  金沢医科大学, 医学部, 教授 (40238895)
Project Period (FY) 2013-04-01 – 2016-03-31
KeywordsIgG4関連疾患 / 線維化
Outline of Final Research Achievements

To quantify the degree of fibrosis in various organs in IgG4 related disease, and to clarify the mechanism of the fibrosis in IgG4 related disease, this study was performed. Pericyte and myofibroblast cells were thought to be related to fibrosis of IgG4 related disease. Compared to non-IgG4 related disease, the degree of fibrosis was significantly higher. It was possible to quantify the degree of fibrosis in IgG4 related disease.

Free Research Field

病理診断学

URL: 

Published: 2017-05-10  

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