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2015 Fiscal Year Final Research Report

Involvement of oxidative stress and check points in CKD-MBD

Research Project

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Project/Area Number 25461247
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Kidney internal medicine
Research InstitutionThe University of Tokushima

Principal Investigator

HAMADA Yasuhiro  徳島大学, 大学院医歯薬学研究部, 教授 (30397830)

Project Period (FY) 2013-04-01 – 2016-03-31
Keywords骨代謝 / 低回転骨
Outline of Final Research Achievements

Diabetes Mellitus is one of the representative diseases to cause chronic kidney disease - mineral and bone disorder (CKD-MBD). The bone disorder of diabetes shows low turnover bone. In order to elucidate the involvement of oxidative stress in low turnover bone, statin, which is a lipid-lowering medication and has anti-oxidative effct, were administered to diabetic animal model. In conclusion, administration of statin improved low turnover diabetic osteopenia.

Free Research Field

腎臓内科学

URL: 

Published: 2017-05-10  

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