2015 Fiscal Year Final Research Report
Regulation of hematopoietic stem cell function by calorie restriction
| Project/Area Number |
25461411
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Hematology
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| Research Institution | Kanazawa University |
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Principal Investigator |
Tadokoro Yuko 金沢大学, がん進展制御研究所, 助教 (00447343)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Keywords | 幹細胞 / カロリー制限 |
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| Outline of Final Research Achievements |
Recent studies have indicated that calorie restriction affects the regulation of tissue specific stem cells. Thus, calorie control has been thought as a novel regulatory machinery of stem cell regulation. In this study, I have investigated how calorie restriction influences regulation of hematopoietic stem cell system. I found that calorie restriction phenotypically increased the number of hematopoietic stem cells, while there is no advantage in stem cell function.
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| Free Research Field |
幹細胞生物学
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