2016 Fiscal Year Final Research Report
Lithium in drinking water and suicide prevention: a survey of JAPAN
| Project/Area Number |
25461734
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Oita University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | リチウム / 自殺率 / 水道水 |
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| Outline of Final Research Achievements |
The aim of the present study was to investigate the association between lithium levels of tap water and suicide rate with adjustment of potential factors affecting suicide in all 785 cities and 23 wards of Tokyo in all over Japan. Standardized mortality rates (SMRs) of suicide for 2010-2015 were averaged and used for suicide rates. Multiple regression analyses were performed to predict total SMRs, male SMRs, and female SMRs using lithium levels of tap water of 808 cities/wards, 8 districts (Hokkaido, Tohoku, Kanto, Chubu, Kinki, Chugoku, Shikoku, Kyushu), and interactions between lithium levels and individual districts as independent factors. As a result, lithium levels significantly and inversely predicted male suicide SMRs, but not female suicide SMRs. The present findings suggest that lithium in tap water may be inversely associated with male suicide rate.
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| Free Research Field |
疫学研究
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