Visualization of the deep perforating artery and related brain changes

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461819
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyoto University
• Principal Investigator: Okada Tomohisa 京都大学, 医学(系)研究科(研究院), 准教授 (30321607)
• Co-Investigator(Kenkyū-buntansha): YAMAMOTO Akira 京都大学, 大学院医学研究科, 助教 (60525567) ; KANAGAKI Mitsunori 京都大学, 大学院医学研究科, 助教 (50378676)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 深部灰白質穿通動脈 / MRアンギオグラフィ

Outline of Final Research Achievements

This research targeted the perforating artery of the deep gray matter. Firstly, its visualization was successfully conducted using a new scan method of FSBB at 3T. The visualization was also confirmed on 7T. Secondly, its pathological changes caused by such factors as hypertension are under analysis now. Thirdly, for structural changes caused by the perforating artery, methodological validation was conducted on volumetry and T1 value quantitation. Diffusion tensor imaging was also conducted to investigate small structures in the brain. Moya-moya disease was selected as a representative case for a pathological condition related to the perforating artery and the investigational results was reported.

Free Research Field

中枢神経系放射線診断学