2016 Fiscal Year Final Research Report
Differentiated imaging of microstructures in brain tumors using phase difference enhanced imaging (PADRE) by high magnetic field MRI system
| Project/Area Number |
25461843
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Osaka City University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2013-04-01 – 2017-03-31
|
| Keywords | PADRE / 位相画像 / 脳腫瘍 |
|---|
| Outline of Final Research Achievements |
Brain tumors influence various microstructures of the brain, which are sometimes essential of biological feature; and these microstructures have a possibility to be imaged separately using phase difference enhanced imaging (PADRE) technique.
In the present study, vascular-enhanced images and myelin-enhanced images were obtained with PADRE technique. In two groups of 11 cases of metastatic brain tumors（age 64.3±13.9）and 31 cases of glioma（WHO grading 2-4）（age 49.6±21.9）, vessels and myelin fibers of cerebral white matter including optic radiations were visually analyzed using the four grade of imaging findings （1: poor; 2: fair; 3: moderate; 4: good）. Delineations of vascular components showed no statistically significant differences between the two groups of metastatic brain tumor and glioma（p=0.56）, while these of optic radiations showed statistically significant（p=0.04）.
|
| Free Research Field |
脳機能画像の開発
|
