Creating experimental dissecting aortic aneurysm model and the evaluation for optimal endovascular procedre using this model

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461879
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kobe University
• Principal Investigator: SUGIMOTO KOJI 神戸大学, 医学部附属病院, 教授 (90314476)
• Co-Investigator(Kenkyū-buntansha): YAMAGUCHI MASATO 神戸大学, 医学部附属病院, 准教授 (10457096) ; SOFUE KEITARO 神戸大学, 医学部附属病院, 講師 (90622027)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 解離性大動脈瘤 / 血管内治療 / IVR

Outline of Final Research Achievements

We previously reported succesfully creating an experimental model of acute type B aortic dissection with minimally invasive endovascular procedure in swine. In this study, we further examined creating more stable acute type B aortic dissection model and choronic dissecting aortic aneurysm model. More stable acute type B aortic dissection model was succesfully created with modified technique. Of the 6 experimental swine, chronic dissecting aortic aneurysm model was successfully created in 3. This experimental model in swine is promising, and should contribute to the study for future therapeutic development for chronic dissecting aortic aneurysm.

Free Research Field

医歯薬学