• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2015 Fiscal Year Annual Research Report

肺腫瘍に対するラジオ波凝固療法と化学療法併用の基礎的研究

Research Project

Project/Area Number 25461887
Research InstitutionOsaka City University

Principal Investigator

大隈 智尚  大阪市立大学, 大学院医学研究科, 講師 (50445029)

Project Period (FY) 2013-04-01 – 2016-03-31
Keywordsラジオ波凝固療法
Outline of Annual Research Achievements

兎肺腫瘍モデルを用いた経皮的ラジオ波凝固療法と化学療法の併用についての基礎研究を行った。肺腫瘍モデルはCTガイド下にVX2腫瘍細胞を注入、1週間後のCTにて腫瘍生着したのを使用した。治療グループは1)抗がん剤単独2)抗がん剤+ラジオ波凝固療法3)ラジオ波単独との比較検討をおこなった。使用抗がん剤はシスプラチン、パクリタキセル、ビノレルビンを使用し、血管新生阻害薬としてベバシズマブの併用をおこなった。統計学的にラジオ波凝固に抗がん剤併用で優位に生存延長した群があることを示し、現在、研究成果をまとめて英文誌に投稿、査読中である。

  • Research Products

    (4 results)

All 2015

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Acknowledgement Compliant: 1 results)

  • [Journal Article] Life-threatening and Rapidly Growing Teratoma in the Anterior Mediastinum.2015

    • Author(s)
      Omachi N, Kawaguchi T, Shimizu S, Okuma T, Kitaichi M, Atagi S, Yoon HE, Matsumura A.
    • Journal Title

      Intern Med

      Volume: 54 Pages: 487-489.

    • DOI

      10.2169/internalmedicine.54.4622

    • Peer Reviewed
  • [Journal Article] Intravascular synovial sarcoma of the pulmonary artery with massive pleural effusion: report of a case with a favorable response to Ifosfamide chemotherapy and palliative radiation therapy.2015

    • Author(s)
      Maekura T, Shimizu S, Kawaguchi T, Morimoto M, Okuma T, Matsui H, Atagi S.
    • Journal Title

      Intern Med

      Volume: 54 Pages: 1095-1098

    • DOI

      10.2169/internalmedicine.54.3624

    • Peer Reviewed
  • [Journal Article] Combination radiofrequency ablation and local injection of the immunostimulant bacillus Calmette-Guérin induces antitumor immunity in the lung and at a distant VX2 tumor in a rabbit model.2015

    • Author(s)
      Hamamoto S, Okuma T, Yamamoto A, Kageyama K, Ueki A, Matsuoka T, Miki Y.
    • Journal Title

      J Vasc Interv Radiol.

      Volume: 26 Pages: 271-278

    • DOI

      10.1016/j.jvir.2014.09.002

    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Small calcifying fibrous pseudotumor of the heart confined to the epicardium.2015

    • Author(s)
      Shimizu S, Funakoshi Y, Yoon HE, Okuma T, Utsumi T, Ito N, Sakaguchi M, Taniguchi K, Eimoto T, Matsumura A.
    • Journal Title

      Cardiovasc Pathol.

      Volume: 24 Pages: 191-193

    • DOI

      10.1016/j.carpath.2014.11.003.

    • Peer Reviewed

URL: 

Published: 2017-01-06  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi