Beam condition dependence of dose monitor calibration factor for proton therapy

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461936
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Shizuoka Cancer Center Research Institute
• Principal Investigator: Kase Yuki 静岡県立静岡がんセンター(研究所), その他部局等, その他 (70455385)
• Co-Investigator(Kenkyū-buntansha): YAMASHITA Haruo 静岡県立静岡がんセンター(研究所), 陽子線治療研究部, 主任研究員 (20399588) ; SAKAMA Makoto 放射線医学総合研究所, 重粒子医科学センター, 研究員 (80455386)
• Co-Investigator(Renkei-kenkyūsha): MIZOTA Manabu 九州国際重粒子線がん治療センター, 物理室, 室長 (60649234) ; Murayama Shigeyuki 静岡県立静岡がんセンター(研究所), 陽子線治療研究部, 部長 (60231635)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 陽子線治療 / 線量モニタ / 照射野効果 / ワブラー法 / 出力係数

Outline of Final Research Achievements

In radiation therapy, it is necessary to preset a monitor unit in an irradiation control system to deliver a prescribed absolute dose to a reference point in the planning target volume. The purpose of this study was to develop a model-based monitor unit calculation method for proton-beam therapy. The absorbed dose at a calibration point per monitor unit had been measured for each beam-specific measurement condition before proton therapeutic irradiation.
In this study, we developed a simplified dose output model and a field-size effect calculation model to obtain the output ratio between a beam-specific dose and a reference field dose, from which a monitor unit for the proton treatment could be derived without beam-specific measurements.

Free Research Field

放射線科学