2015 Fiscal Year Final Research Report
Study of the factors associated with a cause and progression of idiopathic scoliosis
| Project/Area Number |
25462318
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Spinal Injuries Center |
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Principal Investigator |
MAEDA TAKESHI 独立行政法人労働者健康福祉機構総合せき損センター(研究部), その他部局等, 研究員 (80315077)
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| Co-Investigator(Renkei-kenkyūsha) |
OKADA SEIJI 九州大学, 医学研究院, 准教授 (30448435)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 特発性側弯症 |
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| Outline of Final Research Achievements |
The factors associated with a cause and progression of idiopathic scoliosis remain unclear. We examined the relationship between the anteroposterior chest dimension and the Cobb angle in thoracic scoliosis patients, and found that there was a significant correlation between them. We further demonstrated that a rib cage deformity with an imbalanced load to the vertebral body resulted in progressive structural scoliosis by using mice model.
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| Free Research Field |
医歯薬学
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