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2016 Fiscal Year Final Research Report

The Effects of Adrenaline and Vasopressin onPial Microvessels During Global Brain Ischemia-reperfusion Period in Rabbits.

Research Project

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Project/Area Number 25462401
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Anesthesiology
Research InstitutionUniversity of Yamanashi

Principal Investigator

ASANO Nobumasa  山梨大学, 総合研究部, 助教 (30456470)

Co-Investigator(Renkei-kenkyūsha) ISHIYAMA Tadahiko  山梨大学, 総合研究部, 准教授 (90293448)
MASAMUNE Taishi  山梨大学, 総合研究部, 助教 (40324199)
IWASHITA Hironobu  山梨大学, 総合研究部, 助教 (10232670)
KOTODA Masakazu  山梨大学, 総合研究部, 助教 (30530133)
IKEMOTO Koudai  山梨大学, 総合研究部, 助教 (50530127)
KUMAKURA Yasutomo  山梨大学, 総合研究部, 助教 (00530130)
Project Period (FY) 2013-04-01 – 2017-03-31
Keywordscranial window
Outline of Final Research Achievements

Adrenaline and Vasopressin were recommended to use during cardiopulmonary resuscitation. The aims of the present study were to evaluate the direct effects of adrenaline and vasopressin on cerebral pial arterial diameter changes in the normal states and during ischemia-reperfusion period.
Adrenaline and Vasopressin exerted no direct action on cerebral pial artery in the normal state. Adrenaline increased cerebral pial arteriolar diameter at compared with vasopressin and control in the ischemia-reperfusion period.

Free Research Field

anesthesiology

URL: 

Published: 2018-03-22  

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