2016 Fiscal Year Final Research Report
Investigation of pathology of sensorineural hearing loss from redox state and inflammatory cytokines and application for treatment
| Project/Area Number |
25462634
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | 難聴 / レドックス |
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| Outline of Final Research Achievements |
Because genetic factors may contribute partly to the etiologies of inner ear diseases, we investigated the association between genetic polymorphisms located in genes related to the free-radical process or inflammatory pathway and susceptibility to sudden deafness. We found that NOS 3 and uncoupling protein 2 polymorphisms were significantly associated with the risk of sudden deafness.
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| Free Research Field |
医歯薬学
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