2015 Fiscal Year Final Research Report
Multiethnic analysis of Behcet disease and its associated genes in Central Asia
| Project/Area Number |
25462731
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Health Sciences University of Hokkaido |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAMBA Kenichi 北海道大学, 病院, 講師 (70333599)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | ベーチェット病 / 中央アジア / 遺伝子 / ゲノム |
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| Outline of Final Research Achievements |
I delivered special lectures about Behcet disease in Russia, Kazakhstan, and Kyrgyzstan, then made a diagnosis there. We understand that there are some Behcet patients in Russia and Kazakhstan. Most of the patients in Russia are not Russian but the minority groups of Dagestanian, Azerbaijani, Chechen, and Armenian. All of these 4 ethnic groups are Turki living in Caucasus region between Black Sea and Caspian Sea.Their clinical features are similar to those in other countries including Japan.
HLA Class I analysis showed that the frequency of HLA-B51 is high among the patients compared with healthy people. However, the exact frequency of HLA-B51 gene in healthy population is still unknown.
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| Free Research Field |
眼科学
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