2015 Fiscal Year Final Research Report
Individualization of treatment therapy for diabetic macular edema by laser speckle flowgraphy
| Project/Area Number |
25462737
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Tokyo Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YASUDA Kanako 東京医科大学, 医学部, 講師 (70647461)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 糖尿病黄斑浮腫 / 血流 |
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| Outline of Final Research Achievements |
The main cause of diabetic macular edema is considered to be retinal vascular deficiencies, and there are various types of treatment therapies, and also the sensitivity to each therapy is cknown to be case-dependent. In this study, using laser speckle flowgraphy, we successfully evaluate the dynamic change of blood flow volume in the retinal vessels. However, unfortunately, dynamic change of retinal blood flow volume after each treatment did not correlate with visual or morphologicl prognosis. Thus the limitation of this study with evaluation of blood flow volume was clarified. While response to anti-VEGF therapy for diabetic macular edema varies individually, and baseline humor aqueous concentrations of inflammatory cytokines reflect the number of IVR injections in the loading phase required to resolve DME.
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| Free Research Field |
網膜硝子体
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