2016 Fiscal Year Final Research Report
Clinical study of using the platelet-rich plasma for preventing postoperative fistula after palatoplasty
| Project/Area Number |
25463095
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Kindai University (2015-2016)
Kagoshima University (2013-2014) |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Keywords | 口蓋形成術 / ろう孔 / 多血小板血漿 |
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| Outline of Final Research Achievements |
Palatoplasty is the essential treatment to get good nasopharyngeal atresia function. 93% of all palatoplasty patients could have get post operative nasopharyngeal atresia normal funciton. However, anterior hard palate tissue tends to occur fistula for pushback of palate-mucosal tissue. The postoperative fistula incidence ratio after palatoplasty of unilateral cleft and palate patients at our hospital demonstrated 43.7% from 2006 to 2011 and postoperative large fistula have become serious problem. Then we have performed palatoplasty with platelet‐rich plasma which is usable in the treatment of wounds for tissue regeneration and for wound healing for preventing of postoperative fistula and have studied those effects. As that results, the postoperative fistula incidence ratio decreased to 11.1% and there was no case with postoperative large fistula. Therefore, it was suggested that palatoplasty with platelet‐rich plasma would became one useful method to prevent postoperative fistula.
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| Free Research Field |
口腔顎顔面外科
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