2016 Fiscal Year Final Research Report
Development of fundamental therapy for temporomandibular muscle disorders by gastroenterological approach.
Project/Area Number |
25463191
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Orthodontics/Pediatric dentistry
|
Research Institution | Kagoshima University |
Principal Investigator |
Takada Hiroko 鹿児島大学, 医歯学総合研究科, 客員研究員 (80634229)
|
Project Period (FY) |
2013-04-01 – 2017-03-31
|
Keywords | 咀嚼 / 消化管ホルモン / 咀嚼筋障害 / 消化管運動 |
Outline of Final Research Achievements |
Gastrointestinal hormones and 13C-acetate breath test with electrogastrography and electrocardiography was performed in healthy men who ingested a test meal with or without chewing gum. Blood samples for the measurement of glucose, insulin, gastrin, ghrelin, CCK, and GLP-1 were drawn before the meal and at 30-min intervals after the beginning of test meal consumption until the end of the session 240 min later. As a result, no significant difference in gastrointestinal hormones was observed between the two trials in 4 healthy men. A causal relationship between gastrointestinal hormones and temporomandibular muscle disorders was not determined in this study and should be investigated in future studies.
|
Free Research Field |
歯科矯正学
|