Development of phototherapy using lasers and LEDs for the treatment and prevention of periodontitis and peri-implantitis

2016 Fiscal Year Final Research Report

• Project/Area Number: 25463212
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Periodontology
• Research Institution: Tokyo Medical and Dental University
• Principal Investigator: AOKI AKIRA 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 (30302889)
• Co-Investigator(Renkei-kenkyūsha): Ohshima Mitsuhiro 奥羽大学, 薬学部, 教授 (30194145) ; Hiratsuka Koichi 日本大学, 松戸歯学部, 教授 (80246917) ; Komaki Motohiro 東京医科歯科大学, 医歯学総合研究科, 准教授 (30401368) ; Iwasaki Kengo 東京医科歯科大学, 医歯学総合研究科, 講師 (40401351) ; Tsuchida Sachio 千葉大学, 医学部附属病院, 助教 (90410422) ; Taniguchi Yoichi 東京医科歯科大学, 医歯学総合研究科, 非常勤講師 (30648093)
• Research Collaborator: Schwarz Frank Heinrich Heine University, Department of Oral Surgery, Associate Professor ; Sculean Anton University of Bern, Department of Periodontology, Professor ; Coluzzi Donald J. University of California, Department of Preventive and Restorative Dental Sciences, Clinical Professor
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: レーザー / LED / 歯周炎 / インプラント周囲炎 / 歯周ポケット / 細胞 / 細菌 / 抜歯窩

Outline of Final Research Achievements

The following studies were performed to establish the application of phototherapy using light energy such as lasers and LEDs for the treatment and prevention of periodontitis and peri-implantitis. We developed a novel comprehensive periodontal pocket treatment protocol using Er:YAG laser and evaluated its clinical effectiveness, investigated photobiomodulation effect of the Er:YAG laser, clarified the promotion of wound healing of extraction sockets using a low-level diode laser, and demonstrated the bactericidal effect using a combination of blue LED and red dye (rose bengal).

Free Research Field

歯周病学，歯周治療学，レーザー歯学