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2015 Fiscal Year Final Research Report

Organella Computing

Research Project

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Project/Area Number 25540098
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Intelligent informatics
Research InstitutionTokyo Institute of Technology

Principal Investigator

YAMAMURA Masayuki  東京工業大学, 総合理工学研究科, 教授 (00220442)

Co-Investigator(Renkei-kenkyūsha) SUZUKI Yasuhiro  名古屋大学, 情報科学研究科, 准教授 (50292983)
Project Period (FY) 2013-04-01 – 2016-03-31
Keywordsオルガネラ計算 / DNA計算 / 糖鎖計算 / 膜計算 / ナノマシン
Outline of Final Research Achievements

Cells on Earth are classified into Prokaryote and Eukaryote. Prokaryiote cells consist of DNA, protein and other organic materials covered with single membrane, and are specialized to survive given environment. Eukaryote cells consits of various kinds of organera such as nucleus for DNA storage, mitcondria for energy production, Goldgi apparatus for sugarchain production and so on. These double membrane structure of Eukaryote cells are said to be formed through synbiosis of Prokaryote cells. Eukaryote cells have various higher order functions in multicellular organisms rather than survival. This research propose the conceptual framowork for organera computing by using Synthetic Biology techniques on Eukaryote cells and computer simulation. Since it is found difficult to make genetically modified organera, we forcused on nanoscale machines as a component and evolvable artificial life by computer simulation.

Free Research Field

システム科学

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Published: 2017-05-10  

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