2014 Fiscal Year Final Research Report
Analysis of radiation-induced DNA double strand break repair during cell cycle
| Project/Area Number |
25550023
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Risk sciences of radiation and chemicals
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| Research Institution | Ibaraki University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | DNA損傷修復 / 細胞周期 |
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| Outline of Final Research Achievements |
DNA double strand break (DSB) is one of the most serious DNA damage which is often induced by ionizing radiation. To clarify whether DSB repair occurs during just before the cell division stage or not, we developed a site- and time-specific DSB induction system. By using the system, we tried to see the DSB-localizing proteins following DNA damage induction. The experiments are still in progress, but a part of our findings has been published in a scientific journal.
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| Free Research Field |
放射線生物学
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