2015 Fiscal Year Final Research Report
The basic study on effects of long-term feeding of very low-carbohydrate diet on glucose tolerance and safety in the genetic diabetic rats.
| Project/Area Number |
25560053
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits
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| Research Institution | Kagawa University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 糖質制限食 / 糖尿病 / 耐糖能 / 寿命 / 安全性 / 遺伝性糖尿病ラット |
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| Outline of Final Research Achievements |
The effects of long-term feeding of very low-carbohydrate diet on glucose tolerance and safety were studied in the genetic diabetic rats, Goto-Kakizaki (GK) rats. Forty-eight male GK rats (3 weeks of age) were divided by 16 into high-carbohydrate (HC) diet group, high-fat (HF) diet group, and very low-carbohydrate (LC) diet group and bred until all the rats died. The glucose tolerance was confirmed by feeding of LC diet temporarily, but was improved by a long-term feeding. In addition, the mean life span did not differ among the three groups. These results suggest that long-term feeding of LC diet improve glucose tolerance compared with HC and HF diets, but did not influence life span in GK rats.
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| Free Research Field |
栄養学
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