Evaluation of anti-aging food factors by measuring age-related hearing loss in mice

2014 Fiscal Year Final Research Report

• Project/Area Number: 25560066
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Eating habits
• Research Institution: National Agriculture and Food Research Organization
• Principal Investigator: OIKE Hideaki 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所・食品機能研究領域, 主任研究員 (30455307)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 老化 / 加齢性難聴 / マウス / 食事

Outline of Final Research Achievements

We established a evaluation method for anti-aging food factors by measuring age-related hearing loss (AHL) in mice. Drinking of alcohol, caffeine, or artificial sweeteners for 6 months did not affect onset of AHL, however, intake of high fat diets delayed onset of AHL. Shift of meal-timing for 3 months did not affect AHL. Neither deletion of Tas1R3 gene, which code a taste receptor for sweet and umami, altered onset of AHL.

Free Research Field

食品機能学