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2014 Fiscal Year Final Research Report

Development of an insulin treatment supporting system for control of blood glucose of severe patients

Research Project

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Project/Area Number 25560213
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionKawasaki Medical School

Principal Investigator

OGASAWARA Yasuo  川崎医科大学, 医学部, 准教授 (10152365)

Co-Investigator(Kenkyū-buntansha) YADA Toyotaka  川崎医科大学, 医用工学, 講師 (00210279)
NAKAMOTO Hiroshi  川崎医科大学, 医用工学, 助教 (10299183)
Project Period (FY) 2013-04-01 – 2015-03-31
Keywordsインスリン / 血糖値調整 / ICU
Outline of Final Research Achievements

It is important to maintain blood glucose levels within an appropriate range in a treatment of severe patients. The intensive insulin therapy is known to be effective for the treatment of these patients; however, it is required to frequently monitor blood glucose levels and to inject proper amounts of insulin appropriate timings. Recently, a feedback control system for insulin injection has been developed by using the algorithm based on a classic control theory.
In this study, we have developed a noble algorithm based on a multivariable self-regression model for insulin administration. It was confirmed that the new system demonstrated satisfying performance by simulation experiments using a simulator for blood glucose dynamics.

Free Research Field

医用生体工学

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Published: 2016-06-03  

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