Development of Environmentally-friendly Molecular Transformations of Unsaturated Compounds

2014 Fiscal Year Final Research Report

• Project/Area Number: 25620072
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Synthetic chemistry
• Research Institution: Hokkaido University
• Principal Investigator: HIROHISA Ohmiya 北海道大学, 理学(系)研究科(研究院), 准教授 (40508876)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 不飽和化合物 / 銅触媒 / カルボスタニル化 / 水素化

Outline of Final Research Achievements

The researcher examined copper(I)-catalyzed reactions using alkyne substrates. As a result, a copper-catalyzed three-component coupling with alkylboranes, alkynoates, and tributyltin methoxide was developed as a versatile route to trisubstituted alkenylstannanes. Additionally, syn-selective hydrogenation of internal alkynes with molecular hydrogen under the influence of a catalytic amount of copper complexes was achieved.

Free Research Field

有機合成化学