2014 Fiscal Year Final Research Report
Development of methods for quantitative and qualitatve analyses of protein O-GlcNAcylation.
Project/Area Number |
25650003
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Molecular biology
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Research Institution | The University of Tokyo |
Principal Investigator |
KUBOTA Yuji 東京大学, 医科学研究所, 助教 (70614973)
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Project Period (FY) |
2013-04-01 – 2015-03-31
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Keywords | 翻訳後修飾 |
Outline of Final Research Achievements |
O-GlcNAcylation, a kind of protein post-translational modifications, has an important roles in various cellular functions such as cell proliferation and metabolism. Recently, it has been reported that its dysregulation causes such as diabetes and cancers. However, fundamental techniques and methods for the analysis of protein O-GlcNAcylation are insufficient. Therefore, I conducted this study for the purpose of development of new techniques in O-GlcNAc analysis.
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Free Research Field |
分子生物学
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