Trial to identify genes related with fish characters using bioinformatics and genome database

2015 Fiscal Year Final Research Report

• Project/Area Number: 25660151
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Aquatic bioproduction science
• Research Institution: Tohoku University
• Principal Investigator: Suzuki Tohru 東北大学, (連合)農学研究科(研究院), 教授 (70344330)
• Co-Investigator(Kenkyū-buntansha): SAKAI Yoshifumi 東北大学, 大学院農学研究, 准教授 (10277361)
• Co-Investigator(Renkei-kenkyūsha): YOKOI Hayato 東北大学, 大学院農学研究, 助教 (40569729)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 逃避行動 / 多型性 / ゲノム情報 / メダカ / 魚類 / 繰り返し配列 / 脳機能

Outline of Final Research Achievements

One of representative genetic traits required for aquaculture is fish character adequate for breeding, such as non-nervousness. In mammals, polymorphism of single amino acid repeat and microsatellites in promoter region that evolved in the genes related with brain function cause variation of character among strains.
Medaka strains of d-rR and HNI-II have opposing character; the former being tame, while the latter being nervous. Using these two strains, this study aimed at searching the genes correlated with characters of fish strains by using bioinformatics and genome databases. Serotonin receptor, androgen receptor and dopamine receptor were selected as candidate genes. Since polymorphism in repetitive sequences were detected among two strains and wild medaka, it is highly possible that selected three genes are actually correlated with character of strains.

Free Research Field

水産学