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2014 Fiscal Year Final Research Report

Establishment of gene expression system in Bombyx mori

Research Project

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Project/Area Number 25670134
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field General medical chemistry
Research InstitutionHokkaido University

Principal Investigator

HATAKEYAMA Shigetsugu  北海道大学, 医学(系)研究科(研究院), 教授 (70294973)

Project Period (FY) 2013-04-01 – 2015-03-31
Keywordsゲノム医科学
Outline of Final Research Achievements

It is important to use animal models in order to analyze the etiology of human diseases in medical researches. We tried to establish gene expression system in Bombyx more to analyze genetic diseases. We established viral expression system using special Bombyx strains, which can be infected by AcNPV. We made AcNPV virus containing a target gene (GFP gene as a model gene), infected the virus and then could express GFP protein in pupae of Bombyx.

Free Research Field

医歯薬学

URL: 

Published: 2016-09-02  

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