Elucidation of metabolic shift of skeletal muscle during aging and invention of new therapies for sarcopenia

2014 Fiscal Year Final Research Report

• Project/Area Number: 25670437
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Metabolomics
• Research Institution: Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
• Principal Investigator: SHIGEMOTO Kazuhiro 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (40284400)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: サルコペニア / 筋萎縮 / 動物モデル / 代謝 / 筋線維

Outline of Final Research Achievements

Sarcopenia impairs activity of daily living of aged people. For the early prevention or treatment of such conditions, it is required to understand the pathogenesis and invent effective therapies. In this study, we will elucidate the metabolic changes in skeletal muscle during aging and establish the new technologies for developing innovative preventive and therapeutic methods by remodleing the metabolism.

Free Research Field

基礎老化学