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2014 Fiscal Year Final Research Report

The effectiveness and biocompatibility of iodine coated implant

Research Project

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Project/Area Number 25670640
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Orthopaedic surgery
Research InstitutionKanazawa University

Principal Investigator

HIDEJI Nishida  金沢大学, 医学系, 協力研究員 (50569374)

Project Period (FY) 2013-04-01 – 2015-03-31
Keywords抗菌インプラント
Outline of Final Research Achievements

Iodine-coated implants significantly inhibited colonization of the staphylococcus aureus. Biocompatibility of osteoblasts on instruments made by stainless steel, titanium, iodine coated titanium were evaluated. Stainless steel inhibited adhesion of osteoblast on the instruments. On the other hand, there is no significant difference among titanium, titanium with oxidation film, iodine-coated implants. More than 50% of iodine was detected in the implants four weeks after implantation in rabbits. Our results suggest that iodine-coated implants has antibacterial effects without toxicity to normal bone tissues.

Free Research Field

整形外科

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Published: 2016-06-03  

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