Regulation and reconstruction of acquired memories in human microbiota

2014 Fiscal Year Final Research Report

• Project/Area Number: 25670776
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Morphological basic dentistry
• Research Institution: Kyoto University (2014); Tokyo Medical and Dental University (2013)
• Principal Investigator: MARUYAMA Fumito 京都大学, 医学(系)研究科(研究院), 准教授 (30423122)
• Co-Investigator(Kenkyū-buntansha): NAKAGAWA Ichiro 京都大学, 大学院医学研究科, 准教授 (70294113) ; KUROKAWA Ken 東京工業大学, 地球生命研究所, 准教授 (20343246) ; MIMURO Hitomi 東京大学, 医科学研究所, 准教授 (80396887)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: バクテリオファージ / CRISPR / 微生物生態学

Outline of Final Research Achievements

Distribution and structure of the CRISPR, acquired immune mechanisms of bacteria, to bacteriophages, in human microbial flora are assumed that controls the robustness of its flora. As a result, CRISPR unexpectedly exist on the bacteriophage, which has been thought to not be able to coexist. It was revealed that CRISPR are distributed actually in broad range of bacterial species. This indicates that it is necessary to introduce a new concept in helping to continue to clear the robustness of the bacterial flora.

Free Research Field

環境遺伝生態学