2015 Fiscal Year Final Research Report
The evolution of genetical assessment for persistent apical periodontitis.
Project/Area Number |
25670809
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Conservative dentistry
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Research Institution | Osaka University |
Principal Investigator |
Itoh Shousaku 大阪大学, 歯学部附属病院, 講師 (90360495)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Keywords | 根尖性歯周炎 / IL-1B / SNP |
Outline of Final Research Achievements |
The aim of this study is to investigate the relationship between persistent apical periodontitis and SNP of inflammatory cytokine, IL-1B. We investigated the relationship of the SNP in the intron of IL-1B, SNPID:rs1143643. Though the previous reports, from Caucasoid, showed the relationship between the SNP in the intron of IL-1B and persistent apical periodontitis, our study, from Mongoloid, showed no relationship. We concluded that the efficacy of SNP were different among the racial difference, such as Mongoloid and Caucasoid.
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Free Research Field |
医歯薬学
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