The evolution of genetical assessment for persistent apical periodontitis.

2015 Fiscal Year Final Research Report

• Project/Area Number: 25670809
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Conservative dentistry
• Research Institution: Osaka University
• Principal Investigator: Itoh Shousaku 大阪大学, 歯学部附属病院, 講師 (90360495)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 根尖性歯周炎 / IL-1B / SNP

Outline of Final Research Achievements

The aim of this study is to investigate the relationship between persistent apical periodontitis and SNP of inflammatory cytokine, IL-1B. We investigated the relationship of the SNP in the intron of IL-1B, SNPID:rs1143643. Though the previous reports, from Caucasoid, showed the relationship between the SNP in the intron of IL-1B and persistent apical periodontitis, our study, from Mongoloid, showed no relationship. We concluded that the efficacy of SNP were different among the racial difference, such as Mongoloid and Caucasoid.

Free Research Field

医歯薬学