Prevalence and clinical features of restless legs syndrome among Japanese pregnant women

2015 Fiscal Year Final Research Report

• Project/Area Number: 25670973
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Lifelong developmental nursing
• Research Institution: Nagasaki University
• Principal Investigator: ETO Hiromi 長崎大学, 医歯薬学総合研究科(保健学科), 教授 (10213555)
• Co-Investigator(Kenkyū-buntansha): OKA Yasunori 愛媛大学, 医学部附属病院, 准教授 (60419025)
• Co-Investigator(Renkei-kenkyūsha): HORIUCHI Shigeko 聖路加国際大学, 看護学部, 教授 (70157056) ; NISHIHARA Kyoko (公財)労働科学研究所, 研究員 (80172683)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 乳児 / 妊婦 / フェリチン / 睡眠時周期性四肢運動 / RLS / 鉄 / 葉酸 / 乳幼児突然死症候群

Outline of Final Research Achievements

Aims: To determine the prevalence of restless legs syndrome (RLS) among Japanese pregnant women, and clarify correlation between RLS and clinical outcomes. Methods: RLS screening was conducted using the Johns Hopkins Telephone Diagnostic Interview for low-risk 140 and high-risk 81 pregnant women in their third trimester. Blood test and biochemistry results, and delivery outcomes were compared between the RLS group and the control group. Results: RLS was experienced by 22 (15.7%) of the 140 women, and 14 (17.3%) of the 81 women. No significant difference was found for hemoglobin, serum ferratin, serum folate levels and delivery outcomes between the RLS group and the control group. Conclusion: The prevalence of RLS was high in Japanese pregnant women whose pregnancy courses were good with no complications.

Free Research Field

母性看護・助産学