Development of a new continuum model of blood based on cellular scale RBC behaviors

2015 Fiscal Year Final Research Report

• Project/Area Number: 25750155
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Biomedical engineering/Biomaterial science and engineering
• Research Institution: Tohoku University
• Principal Investigator: Omori Toshihiro 東北大学, 工学(系)研究科(研究院), 助教 (10633456)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 計算生体力学 / 赤血球 / 血流

Outline of Final Research Achievements

Blood is a dense suspension of red blood cells (RBCs), and RBC behaviors strongly affect mass transport of blood flow. Thus, we need to consider micro scale RBC motions when we discuss the mass transport of blood flow. However, in many cases, blood was assumed as a homogeneous liquid in former studies. Then, we need to develop a completely new continuum model of blood, which is based on cellular scale RBC behaviors. In this study, we developed a computational model of red blood cells using a finite element-boundary element coupling method, and by using the developed RBC model, we calculated a particle stress tensor and shear-induced diffusion of red blood cells in order to develop a new continuum model of blood.

Free Research Field

計算生体力学