Effects of fiber-rich diet with brown rice on endothelial function

2016 Fiscal Year Final Research Report

• Project/Area Number: 25750346
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Applied health science
• Research Institution: Shiga University of Medical Science
• Principal Investigator: KONDO KEIKO 滋賀医科大学, 医学部, 特任助教 (20566567)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Keywords: 食事介入 / 玄米 / 血管内皮機能 / 2型糖尿病

Outline of Final Research Achievements

Twenty-eight patients with type 2 diabetes mellitus were randomly assigned to a brown rice (n=14) or white rice (n=14) diet and were followed for 2 months. After intervention, both groups were followed by white rice diet for 2 months.
In the brown rice group, the intake of dietary fiber increased after the intervention and decreased after the follow-up period. The levels of fasting plasma glucose, glycoalbumin, and, total and LDL-cholesterol improved after the intervention and returned to the baseline levels after the follow-up period in brown rice group. Endothelial function significantly improved after the intervention and these effects were sustained after the follow-up period in the brown rice group, although metabolic parameters were returned to the baseline levels after the follow-up period.
This study suggested the intervention with brown rice improves endothelial function. The effect was sustained for an additional 2 months after stopping the intervention in type 2 diabetes.

Free Research Field

臨床栄養学