2015 Fiscal Year Final Research Report
Synthesis of cycloalkenes utilizing unconventional reactivity of magnesium carbenoids
| Project/Area Number |
25810030
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Organic chemistry
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | マグネシウムカルベノイド / 環化反応 / 求核性 / 求電子性 / カップリング反応 / シクロアルケン / DFT計算 |
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| Outline of Final Research Achievements |
Magnesium carbenoids are reactive intermediates in which the magnesium and chlorine atoms are attached to the carbon atom. Magnesium carbenoids can act not only as nucleophiles but also as electrophiles. I developed intramolecular reactions leading to the formation of various cyclic compounds including cycloalkenes utilizing the ambiphilic reactivity of magnesium carbenoids. From the results of DFT calculations of magnesium carbenoids, I found that the molecular geometry of magnesium carbenoids deviated from that of typical organic molecules and that the structural features of magnesium carbenoids contributed to their unconventional reactivity.
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| Free Research Field |
有機金属化学
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